To protect adjacent columns, right-click on the first column’s heading and drag the selection rightwards or leftwards.For protecting the single column, click on the column’s letter and select it.To lock columns in excel, you need to do the following things: You can also lock the cells via selecting format cells.How to lock particular cells in a worksheet? Now choose all the cells on which you don’t want to apply a locking feature.If you want to make any changes then it will show an error.Click on the protect sheet icon and then ok.In the review tab, you will find the protect sheet option.Look for the review tab located at the ribbon.How to lock all the cells in a worksheet? Here we have given the step-by-step process to lock and unlock the cells. To protect your workbook or worksheet, you can use the protect sheet option or lock option by which the user can not make any changes in the worksheet. Here we have provided step by step process that will help you in locking cells in excel. Now you must be in a hurry to know how to lock cells in Excel (Mac or Windows) so they don’t move when you scroll. To perform the editing of the cells, you need to unlock those cells. You cannot perform any editing on those cells. If you are protecting a worksheet, then that means you are locking all the cells.